Product BioInks
BioInk Consumables
Black Drop’s ready-to-use hydrogels mimic the natural cell environment, ensuring high viability and easy 1:1 mixing with cell suspensions. Offered in five classes, they support diverse applications from regenerative medicine to drug development.
BioInks
Bioinks are the foundational materials used in 3D bioprinting to create functional, living tissue structures. They combine cells with water-swollen polymer networks (hydrogels) to enable precise three-dimensional placement during bioprinting, high post-printing cell viability, and tissue-like behavior after cultivation. To fine-tune and enhance mechanical or biological properties, additives can be incorporated in the bioink matrix. Our advanced hydrogel formulations are designed to mimic the natural cellular environment, ensuring optimal performance across a range of research applications from regenerative medicine to animal-free drug development.
Hydrogel Drop-Colors
Cure Drop
Cure Drop is a photocurable and animal-free hydrogel based on recombinant collagen peptides. Based on LAP photocrosslinker it can be crosslinked using 365 or 405 nm photocuring wavelength.
Blue Drop
Blue Drop Hydrogels are polysaccharide-based and derived from plants. The crosslinked constructs can possess high mechanical strength, while the polymers are relatively bioinert making them well suited for encapsulation applications or as base material for a hydrogel blend.
Blue Drop Fiber Blast
Blue Drop FiberBlast! are Blue Drop hydrogels that are blended with bovine collagen microfibers. These microfibers enhance material properties in three ways.
Green Drop
Green Drop hydrogels are protein-based and derived from mammals. The crosslinked constructs possess high biological relevance and are often blended with Blue Drop Hydrogels to improve mechanical properties.
Red Drop
Red Drop hydrogels are synthetic or protein-based. The crosslinking of bioprinted constructs is not permanent, so that the structures can be dissolved post-printing under certain conditions. This enables the use as sacrificial material, e.g. to create cavities or perfusable vessel-like in bioprinted tissue models.
Cure Drop
Cure Drop is a photocurable and animal-free hydrogel based on recombinant collagen peptides. Based on LAP photocrosslinker it can be crosslinked using 365 or 405 nm photocuring wavelength.
Properties
Available Concentrations (w/v)*: 6%
Suitable Bioprinting Strategies:
Blue Drop
Blue Drop Hydrogels are polysaccharide-based and derived from plants. The crosslinked constructs can possess high mechanical strength, while the polymers are relatively bioinert making them well suited for encapsulation applications or as base material for a hydrogel blend.
Blue Drop Agarose
Agarose is a thermo-crosslinkable polymer that is derived from red algae. It is a standard hydrogel in biology which is also used for DNA electrophoreses.
Available Concentrations (w/v)*:
Suitable Bioprinting Strategies:
Available Concentrations (w/v)*:
Suitable Bioprinting Strategies:
Blue Drop Alginate
Alginate is a ionically crosslinkable polymer that is derived from brown algae. Alginate bioinks can be printed using a support bath (FRESH) or free-standing when they are blended with rheology modifiers such as Nanocellulose.
Available Concentrations (w/v)*:
Suitable Bioprinting Strategies:
*divide by 2 to get final bioink concentrations due to 1:1 mixing with cell suspension.
Blue Drop Fiber Blast
Blue Drop FiberBlast! are Blue Drop hydrogels that are blended with bovine collagen microfibers. These microfibers enhance material properties in three ways.
First, the post-printing mechanical strength of bioprinted constructs increases by up to +88% for tensile and +116% in compressive strength compared to pure Blue Drop hydrogels. Meanwhile, viscosity in liquid state does not change significantly, so that the same printing parameters can be used.First, the post-printing mechanical strength of bioprinted constructs increases by up to +88% for tensile and +116% in compressive strength compared to pure Blue Drop hydrogels. Meanwhile, viscosity in liquid state does not change significantly, so that the same printing parameters can be used.
Second, shape rentention while incubation can be enhanced significantly by reducing shrinkage of the printed constructs. After 28d a shape retention of up to 92% is observed.
Third, biological properties are enhanced compared to pure Blue Drop hydrogels, since the bovine microfibers act as physiologically relevant site for cell attachment within the bioprinted constructs.
FiberBlast! Microfibers
Blue Drop Agarose FiberBlast!
Blue Drop Alginate FiberBlast!
*divide by 2 to get final bioink concentrations due to 1:1 mixing with cell suspension.
**divide by 4 to get final bioink concentrations due to 1:1 mixing with cell suspension and additional 1:1 mixing with fiber-suspension.
Green Drop
Green Drop hydrogels are protein-based and derived from mammals. The crosslinked constructs possess high biological relevance and are often blended with Blue Drop Hydrogels to improve mechanical properties.
Green Drop Collagen
Collagen is the most abundant protein in the human extracellular matrix. Green Drop Collagen is a Type I bovine Collagen. It is produced under very mild conditions, preserving its natural fibrillogenesis potential. By using specific fibrillation buffers, the mechanical properties of the printed construct can be fine-tuned from soft to very hard.
Available Concentrations (w/v)*:
Suitable Bioprinting Strategies:
Green Drop Fibrinogen
Fibrinogen is a glycoprotein that is produced in the liver and plays a crucial role in blood coagulation. It can be enzymatically crosslinked to Fibrin using Thrombin.
Available Concentrations (w/v)*:
Suitable Bioprinting Strategies:
*divide by 2 to get final bioink concentrations due to 1:1 mixing with cell suspension.
Red Drop
Red Drop hydrogels are synthetic or protein-based. The crosslinking of bioprinted constructs is not permanent, so that the structures can be dissolved post-printing under certain conditions. This enables the use as sacrificial material, e.g. to create cavities or perfusable vessel-like in bioprinted tissue models.
Red Drop Gelatin
Red Drop Gelatin is derived from porcine collagen and crosslinks thermally. It gelifies when it gets cooled but can be liquified again when heated above the sol-temperature.
Available Concentrations (w/v)*:
Suitable Bioprinting Strategies:
Get the Bioink Specs
Detailed specifications of our cell-friendly hydrogel
formulations for high-performance bioprinting.
BioInks for Every Application
High-quality, ready-to-use bioinks optimized for reliable cell growth and advanced bioprinting results.